Archiv für Februar 2006

Happy coronary patients

Februar 06, 2006 - Markus Hoenicka
A recent report in the section "Opinions and Hypotheses" of the Journal Chest suggests the use of Type-5 phosphodiesterase inhibitors in coronary artery bypass grafting. According to the reviewed data, a 100mg-dose per day is well suited to inhibit platelet aggregation and vasospasms, the two most common and most dangerous complications of coronary artery bypass grafting. The best known of these Type-5 phosphodiesterase inhibitors is sildenafil citrate, better known as - Viagra. It just so happens that this 100mg dose is what most patients with erectile dysfunction need to have some fun again. The article does not discuss what the patients are supposed to do with their (in this case unwanted) arousal if the dose kicks in.

BTW sildenafil citrate has originally been tested for use against pulmonary hypertension. That "other" effect of the substance was only detected after the volunteers of a clinical trial kept on asking for more.